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tag stem cell niche cell molecular biology

Advanced Spatial Tools Map Hematopoietic Stem Cell Niches
Niki Spahich, PhD | Jan 15, 2024 | 4 min read
New technologies and archival tissue biopsy samples enable exploration of changes in the bone marrow as people age.
3D medical illustration showing acute lymphoblastic leukemia cells and red blood cells in circulation.
Niche Interactions Lock Down Leukemia Cells
Deanna MacNeil, PhD | Sep 24, 2023 | 3 min read
Researchers unravel the mystery of epithelial to mesenchymal transition in acute lymphoblastic leukemia with co-culture techniques, CRISPR-screening, and RNA sequencing.
A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
Understanding the Stem Cell Niche
The Scientist Marketing Team | Oct 11, 2015 | 1 min read
The Scientist brings together a panel of experts to discuss interactions between stem cells and external cues, and the role of the stem cell niche in development and disease. 
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Characterizing a stem cell niche
Jonathan Weitzman(jonathanweitzman@hotmail.com) | Sep 12, 2002 | 1 min read
A functional genomic approach has been used to investigate a stem-cell-supportive stromal cell line.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Decoding the Cellular Secrets of the Endometrium 
Deanna MacNeil, PhD | Jan 16, 2024 | 3 min read
Endometrial organoids and single cell analyses helped uncover the molecular mechanisms of a rare uterine condition.

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