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image: Next Generation: Fat-Targeted Gene Knockdown

Next Generation: Fat-Targeted Gene Knockdown

By | October 5, 2014

A small peptide helps a silencing construct home in on the adipocytes of obese mice.

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image: FDA OKs siRNA Ebola Drug

FDA OKs siRNA Ebola Drug

By | September 23, 2014

The US Food and Drug Administration gives the green light to deploy an experimental short interfering RNA treatment against Ebola.

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image: Head Scratchers

Head Scratchers

By | September 1, 2014

Many natural phenomena elude our understanding.

5 Comments

image: The Second Coming of RNAi

The Second Coming of RNAi

By | September 1, 2014

Now showing clinical progress against liver diseases, the gene-silencing technique begins to fulfill some of its promises.

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image: Roche Set to Buy RNAi Firm

Roche Set to Buy RNAi Firm

By | August 6, 2014

The Swiss pharmaceutical giant will reportedly pay $450 million for a Danish biotech company that develops drugs that silence microRNAs.

2 Comments

image: Unraveling the Female Fruit Fly Mating Circuit

Unraveling the Female Fruit Fly Mating Circuit

By | July 2, 2014

Three teams identify different components of the female Drosophila nervous system that govern mating behaviors.

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image: Exploring the Roles of Enhancer RNAs

Exploring the Roles of Enhancer RNAs

By | May 7, 2014

Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.

1 Comment

image: Fighting Viruses with RNAi

Fighting Viruses with RNAi

By | October 10, 2013

The long-debated issue of whether mammals can use RNA interference as an antiviral defense mechanism is finally put to rest.

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image: RNAi Remedy Lowers Cholesterol

RNAi Remedy Lowers Cholesterol

By | October 3, 2013

A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.

1 Comment

image: Gene Silencing Is Golden

Gene Silencing Is Golden

By | August 1, 2013

A beginner’s how-to on RNAi screening in mammalian cells

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