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image: RNAi’s Future in Drug-Target Screening

RNAi’s Future in Drug-Target Screening

By | April 17, 2017

A recent CRISPR study contradicted years of RNA interference research on a well-studied cancer drug target. But is it the last nail in the coffin for RNAi as a screening tool? 

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image: RNA Interference Between Kingdoms

RNA Interference Between Kingdoms

By | February 1, 2017

Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.

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image: Oligonucleotide Therapeutics Near Approval

Oligonucleotide Therapeutics Near Approval

By | December 1, 2016

Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.

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image: Gut Bacteria Vectors

Gut Bacteria Vectors

By | June 1, 2016

Researchers mix bacteria genetically engineered to express double-stranded RNA into insect food.

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image: Questions Over <em>C. elegans</em> Life Span Factors

Questions Over C. elegans Life Span Factors

By | June 1, 2016

A recent paper challenges earlier findings that germline factors expressed in normal body cells influence life span in C. elegans.

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image: Gut Bacteria for Insect RNAi

Gut Bacteria for Insect RNAi

By | June 1, 2016

Lacing insect food with microbes encoding double-stranded RNAs can suppress insect gene expression.

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image: Dial It Up, Dial It Down

Dial It Up, Dial It Down

By | March 1, 2016

Newer CRISPR tools for manipulating transcription will help unlock noncoding RNA’s many roles.

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image: Funding Ban for Plant Biologist

Funding Ban for Plant Biologist

By | January 26, 2016

Olivier Voinnet, who has corrected and retracted several papers, cannot receive Swiss government grants for three years.

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image: Report: Plant Biologist Guilty of Misconduct

Report: Plant Biologist Guilty of Misconduct

By | July 10, 2015

Investigators find that RNAi researcher Olivier Voinnet willfully misrepresented data published in several journals.

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image: Improving Crops with RNAi

Improving Crops with RNAi

By | June 1, 2015

RNA interference is proving to be a valuable tool for agriculture, allowing researchers to develop pathogen-resistant and more-nutritious crops.

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