RNAi

Institutions where RNA interference scientist Olivier Voinnet has worked are looking into allegations of misconduct.

Runners up in the Top 10 Innovations of 2014 competition

A small peptide helps a silencing construct home in on the adipocytes of obese mice.

The US Food and Drug Administration gives the green light to deploy an experimental short interfering RNA treatment against Ebola.

Many natural phenomena elude our understanding.

Now showing clinical progress against liver diseases, the gene-silencing technique begins to fulfill some of its promises.

The Swiss pharmaceutical giant will reportedly pay $450 million for a Danish biotech company that develops drugs that silence microRNAs.

Three teams identify different components of the female Drosophila nervous system that govern mating behaviors.

Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.

The long-debated issue of whether mammals can use RNA interference as an antiviral defense mechanism is finally put to rest.

A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.

The cell detains potentially harmful RNA messages in the spliceosome long enough to create interfering RNAs against the aberrant messages.

A beginner’s how-to on RNAi screening in mammalian cells

As reproductive tissues age, DNA repair mechanisms become less efficient, causing genomic damage to accumulate.

Gregory Hannon believes in taking risks—an approach that’s enabled him to make exciting new discoveries in the world of small RNAs.

Microscopic sponges made entirely of RNA enable efficient gene silencing.

Drug efficacy and resistance mechanisms shine a light on how drugs enter cells, which could facilitate the development of new sleeping-sickness treatments. 

With an eye to understanding animal regeneration, Alejandro Sánchez Alvarado has turned a freshwater planarian into a model system to watch.

A unique virus and the worm it infects turn up in an orchard outside of Paris.