immunology

Some patients could suppress the virus without antiretroviral therapy for months after the drug infusions.

Nine of the most recent retractions from AACR journals are for papers coauthored by embattled cancer researcher Bharat Aggarwal.

Immune cells travel through these passageways to get to injured tissue quickly, researchers say.

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

Phages that die during bacterial invasion help other viruses defeat the microbes’ immune responses.

Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.

A study of Shuar children in Ecuador provides a window into how the human body responds to infection in the sorts of conditions that shaped our species’ evolution.

Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.

Vaccination reduced the risk of death by two-thirds for children with no other health problems.  

The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.

Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  

Researchers found a previously undiscovered hepadnavirus in an immunocompromised cat.

Sequencing of a single gene can spot patients with a dangerous form of mycosis fungoides better than other prognostic tests.  

Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  

By combining two new microscopy technologies, researchers filmed immune cells toiling away in the inner ear of a living zebrafish.

Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.