Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.
Organelles isolated from two types of neurons and a nonneuronal astrocyte in the mouse cerebellum showed varying levels of proteins, hinting at functional differences.
Studying how neural crest cells journey through the embryo, this Caltech developmental biologist has revealed how they form major cell types, including peripheral neurons, bone, and smooth muscle.
The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the development of disease.
Of Disciplines Author: Ricki Lewis Sometimes in science, the best way to move forward is to take a long look backward. For discoveries and data to be put into context and used as springboards for future inquiry, investigators must periodically synthesize and reflect on what has been accomplished, and determine what remains to be learned. A review article is one way to chart the evolution of a scientific discipline. Science has a rich review literature. Of 3,383 journals surveyed in the 1994 Sc
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.