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Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA.  

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image: Rare T Cells Fight Cancer

Rare T Cells Fight Cancer

By | May 1, 2017

A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.

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image: Infographic: How the Zebrafish Got Its Stripes

Infographic: How the Zebrafish Got Its Stripes

By | May 1, 2017

Immune cells called macrophages shuttle cellular messages in the skin.

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Studies of infected rhesus monkeys reveal the virus’s long-term hiding places in the body.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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