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Targeted Comparative Sequencing Illuminates Vertebrate Evolution
Ricki Lewis | Dec 8, 2002 | 6 min read
Image: Courtesy of Elliott Marguiles  PIPS ON PARADE: Researchers used a MultiPipMaker to show the alignments, expressed as percent identity plots, between a human reference sequence and several other species. This is a 20 kb region surrounding exon 2 of the MET gene. Gap-free alignable segments are represented as horizontal lines along the human reference sequence; the line's height represents the identity of that alignment. Aristotle envisioned humanity as the pinnacle of a "Great Chai
Inspired by Nature
Daniel Cossins | Aug 1, 2015 | 10+ min read
Researchers are borrowing designs from the natural world to advance biomedicine.
The Hidden Side of Sex
Patricia L.R. Brennan | Jul 1, 2014 | 10+ min read
Sexual selection doesn’t end when females choose a mate. Females and males of many animal species employ an array of tactics to stack the deck in their reproductive favor.
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C
Intelligent Redesign
Ishani Ganguli | Aug 1, 2006 | 7 min read
FEATURELab Design   Main image: © Getty ImagesSmaller images: Justin MacNochie Photography/SmithgroupWith billions being spent on new labs and renovations, do shinier labs really make for better science? BY ISHANI GANGULIARTICLE EXTRASRelated Articles:Lab Rehab Redesign and the Bottom Line It's Easy Going GreenAnatomy of an energy-sustainable lab renovationWeb Extra:Lab Rehab: Laying out other options
Scientists Debate RNA's Role At Beginning Of Life On Earth
Ricki Lewis | Mar 30, 1997 | 9 min read
Sidebar: RNA's Role at Beginning of Life - For Further Information Before there was life, there were chemicals. The idea that ribonucleic acid (RNA), because of its catalytic capability and multiple roles in protein synthesis, was the chemical that led directly to life is termed the RNA world hypothesis. Although the phrase "RNA world" is generally attributed to Walter Gilbert, Harvard University's Carl M. Loeb University Professor, in a short 1986 paper, the idea of RNA's importance at the beg

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