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In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse. 

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Oncologists have raised concerns about a mouse study that suggests the vaccine for human papillomavirus could cause brain damage.

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image: Viral Immunotherapy for Melanoma

Viral Immunotherapy for Melanoma

By | May 28, 2015

Phase 3 data from a clinical trial show a positive response to a melanoma treatment based on a modified herpesvirus.

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image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

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image: Opinion: Making Cancer Vaccines Work

Opinion: Making Cancer Vaccines Work

By | March 31, 2015

Armed with the right adjuvant system, vaccines are poised to tackle one of the world’s most intractable diseases. 

4 Comments

image: Week in Review: June 23–27

Week in Review: June 23–27

By | June 27, 2014

Tracking chikungunya virus; reconsidering wood decay-based fungal classification; ASC specks spread inflammation; antibiotic tolerance in E. coli; RIKEN review yields corrections

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image: Targeted Brain Cancer Vaccine

Targeted Brain Cancer Vaccine

By | June 25, 2014

Mouse study demonstrates the ability of a cancer vaccine targeted against a specific oncogenic mutation to elicit a protective anti-tumor immune response. 

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image: Deploying the Body’s Army

Deploying the Body’s Army

By | April 1, 2014

Using patients’ own immune systems to fight cancer

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image: A Universal Cancer Vaccine?

A Universal Cancer Vaccine?

By | April 10, 2012

A vaccine that targets 90 percent of all cancers shows promise in early clinical trials.

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image: Cancer Immunotherapy Pioneer Dies

Cancer Immunotherapy Pioneer Dies

By | December 2, 2011

Lloyd Old, a researcher and former administrator of two cancer research institutes, passed away this week.

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