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tag spinal cord injury immunology cell molecular biology

Plugging Up the Injured Spinal Cord
Douglas Steinberg | Dec 9, 2001 | 7 min read
After spending the early 1970s studying regeneration in the Xenopus frog tadpole's optic nerve, Paul J. Reier began to ponder how mammalian spinal cord injuries (SCIs) might heal. Eventually, the junior professor at the University of Maryland School of Medicine chose to enter an emerging field: fetal cell transplantation into the spinal cord. A colleague called the career move crazy--a judgment that Reier now admits wasn't totally unwarranted. "The spinal cord injury field was clouded by pessimi
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
Whither Cell Biology?
Richard Hynes | Dec 10, 2000 | 6 min read
Illustration: A. Canamucio Cell biology has become the third overlapping core discipline of modern biology, along with biochemistry and genetics. Progress over the century--since E.B. Wilson's classic book1 elegantly framed many of the questions of cell biology--has relied on advances in technology and yielded fascinating insights into the ways that cells work. We now have an unprecedented understanding of the structure, organization, and functions of cells. As the number of completed ge
Immune Cell–Stem Cell Cooperation
Sarthak Sinha, Jeff Biernaskie, and Waleed Rahmani | Jul 1, 2016 | 10+ min read
Understanding interactions between the immune system and stem cells could pave the way for successful stem cell–based regenerative therapies.
Bespoke Stem Cells for Brain Disease
Nsikan Akpan | Jan 14, 2013 | 3 min read
Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez, PhD | May 12, 2022 | 3 min read
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
Hollow Fiber Bioreactor Systems Increase Cell Culture Yield
Holly Ahern | Feb 18, 1990 | 4 min read
One of the most important advances in the field of cell biology came in the early 20th century, with the discovery that plant and animal cells could survive - and even replicate - outside the living organism. In 1907, R.G. Harrison, a neurobiologist trying to prove that nerve fibers were actually outgrowths of single cells, chopped up spinal cord tissue and added it to clotted plasma in a humidified growth chamber. The nerve cells from this crude explant not only grew and divided in this enviro
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016 | 10+ min read
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
Bear paw dusted in snow
Hibernating Bears Provide Clue to Preventing Serious Clots in Humans
Natalia Mesa, PhD | Apr 13, 2023 | 3 min read
Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.

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