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tag spinal cord injury developmental biology culture

Japan Approves iPS Cell Therapy Trial for Spinal Cord Injury
Catherine Offord | Feb 18, 2019 | 1 min read
The treatment will be tested in a handful of patients who suffered nerve damage in sports or traffic accidents.
Scientists Strike a Cord
Rabiya Tuma | Feb 9, 2003 | 6 min read
Courtesy of SR Eng  BABY STAINS: The head of a transgenic murine embryo in which a marker enzyme has been specifically expressed in the sensory neurons of the trigeminal and dorsal root ganglia. The marker allows staining of the projections of these neurons into, among other areas, the hindbrain and spinal cord. (S.R. Eng et al., "Defects in sensory axon growth precede neuronal death in Brn3a-deficient mice," J Neurosci, 21:541-9, 2001.) Somewhere in the 200 million bases of the human ge
Fresh asparagus sliced horizontally, revealing inner microchannel structure.
Food for Thought: A Recipe for Regenerating Nerves
Iris Kulbatski, PhD | Oct 23, 2023 | 3 min read
Al dente asparagus stalks may hold the key to successful neural stem cell therapy for repairing injured axons.
Bear paw dusted in snow
Hibernating Bears Provide Clue to Preventing Serious Clots in Humans
Natalia Mesa, PhD | Apr 13, 2023 | 3 min read
Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.
The Neurobiology of Rehabilitation
Ricki Lewis | Jun 29, 2003 | 10+ min read
Courtesy of Eric D. Laywell SPHERES OF PROMISE These neurospheres, clusters of cells in culture derived from the CNS of mice, are stained with antibodies against a neuronal protein (red), and a astrocyte protein (green). They have a nuclear counterstain (blue). The brain and spinal cord were once considered mitotic dead ends, a division of neurons dwindling with toddlerhood, with memory and learning the consequence of synaptic plasticity, not new neurons. But the discovery of neural stem
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016 | 6 min read
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Bespoke Stem Cells for Brain Disease
Nsikan Akpan | Jan 14, 2013 | 3 min read
Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.
Neural Tissue Engineering
Aileen Constans | Jun 20, 2004 | 8 min read
GETTING ON YOUR NERVES:Left: courtesy of Anthony Windebank; right courtesy of Christine SchmidtTo facilitate nerve regrowth, tissue engineers employ biodegradable polymer scaffolds. Shown at left, a micrograph of an actual scaffold used to stimulate spinal cord regeneration in rats. Center, a piece of neural tissue grows on an electrically conductive polymer used primarily for peripheral nerve repair (image colored for effect). At right, stained section of a peripheral nerve showing axons in red
How Groups of Cells Cooperate to Build Organs and Organisms
Michael Levin | Sep 1, 2020 | 10+ min read
Understanding biology’s software—the rules that enable great plasticity in how cell collectives generate reliable anatomies—is key to advancing tissue engineering and regenerative medicine.
Lizard on glass tank
Engineered Stem Cells Grant Geckos “Perfectly” Regenerated Tails
Chloe Tenn | Nov 5, 2021 | 4 min read
Geckos injected with neural stem cells modified to block cartilage growth developed the skeletal and nervous components normally lacking from regrown tails.

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