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image: Valerie Horsley Gets Under Skin

Valerie Horsley Gets Under Skin

By | May 1, 2017

The Yale University cell and molecular biologist is probing the deep mysteries of epidermal cells.

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image: Infographic: Proteasome Basics

Infographic: Proteasome Basics

By | May 1, 2017

The structure and function of the cell's protein-degrading machine

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Studies of infected rhesus monkeys reveal the virus’s long-term hiding places in the body.

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image: Image of the Day: Fanged Fish

Image of the Day: Fanged Fish

By | April 14, 2017

Poisonous fang blennies (Meiacanthus) are only around 2 inches long but, with their tiny fangs, they can inject predators with a venom that has potent hypotensive effects.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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