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tag sexual antagonism microbiology genetics genomics developmental biology

Researchers Blast Open Pathogen Genome
Barry Palevitz | Aug 18, 2002 | 6 min read
Image: Courtesy of Tim Elkins BRUTE FORCE: Remnant of an appressorium formed on Mylar. The appressorium produced a peg-like extension that penetrated the film, leaving a round hole. (Reprinted with permission, Annual Review of Microbiology, 50:491-512, 1996.) "The Lord shall smite thee with a consumption, and with a fever, and with an inflammation, and with an extreme burning, and with the sword, and with BLASTING, and with mildew; and they shall pursue thee until thou perish." Deuteronom
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Genetic Testing's Political Implications Must Be Addressed
Dan Burk | Jul 20, 1997 | 6 min read
The recent public apology by President Clinton on behalf of the United States government to survivors of the Tuskegee syphilis experiments was intended to close the door on one of the most scandalous instances of officially sanctioned scientific misconduct in the annals of biomedical research. Yet, while the apology may bring closure to the particular incident, it stands as a stark reminder of the history that has led many minorities to distrust supposedly objective scientific research. Betraye
Switch Master: A Profile of Barbara Meyer
Diana Kwon | Jan 13, 2020 | 9 min read
Working with bacteriophages and nematodes, the University of California, Berkeley, molecular biologist uncovered a role for genetic switches in early development.
The AIDS Research Evaluators
Lynn Gambale | Jul 9, 1995 | 6 min read
Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don
The Rodent Wars: Is a Rat Just a Big Mouse?
Ricki Lewis | Jul 4, 1999 | 5 min read
Sometimes it seems as if genome projects are cropping up everywhere.1 But until costs come down, limited resources are being largely concentrated into what Joseph Nadeau, professor of genetics at Case Western Reserve University School of Medicine, calls "the genome seven," an apples-and-oranges list of viruses, bacteria, fungi, Arabidopsis thaliana, Drosophila melanogaster, Caenorhabditis elegans, and mouse, with Homo sapiens in its own category.2 Researchers widely acknowledge that in the rod
Top Ten Innovations 2011
The Scientist | Jan 1, 2012 | 10+ min read
Our list of the best and brightest products that 2011 had to offer the life scientist
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
New Era in Vaccine Development
Nadia Halim | Apr 16, 2000 | 6 min read
When all fails, try a new attack. That's exactly what researchers do when they use genome sequence data to develop vaccine candidates against the most difficult pathogenic adversaries. Recent efforts are revealing previously unknown microbial genes that may encode proteins important in triggering immunity. "Whole-genome data provides insight into all the features of [organisms] including access to virtually every single antigen that may provoke an immune response," explains Michael Gottlieb, pa

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