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image: Cortical Census

Cortical Census

By | November 26, 2015

Scientists document the characteristics and connections of mouse neocortical neurons to establish the most detailed microcircuit map to date.

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image: Fatal-Disease Drug in Limbo

Fatal-Disease Drug in Limbo

By | November 25, 2015

A panel of experts advised the US Food and Drug Administration that BioMarin Pharmaceutical has not demonstrated efficacy of its new drug for Duchenne muscular dystrophy.

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image: How Gastric Bypass Can Kill Sugar Cravings

How Gastric Bypass Can Kill Sugar Cravings

By | November 19, 2015

A type of bariatric surgery eliminates gut-to-brain signals that trigger sugar highs, a mouse study shows.  

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image: Birth of the Skin Microbiome

Birth of the Skin Microbiome

By | November 17, 2015

The immune system tolerates the colonization of commensal bacteria on the skin with the aid of regulatory T cells during the first few weeks of life, a mouse study shows.

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image: Blood-Gut Barrier

Blood-Gut Barrier

By | November 12, 2015

Scientists identify a barrier in mice between the intestine and its blood supply, and suggest how Salmonella sneaks through it.

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image: Breaching the Blood-Brain Barrier

Breaching the Blood-Brain Barrier

By | November 11, 2015

Researchers deliver cancer-fighting drugs to a patient’s brain via the bloodstream, penetrating the blood-brain barrier for the first time.

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image: Week in Review: November 2–6

Week in Review: November 2–6

By | November 6, 2015

How Ebola hides from immune cells; gut microbes’ role in immunotherapy response; new mechanisms of hearing loss; butterflies use milkweed toxins to ward off predators

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image: Microbes Play Role in Anti-Tumor Response

Microbes Play Role in Anti-Tumor Response

By | November 5, 2015

Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.

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image: New Route to Hearing Loss Mapped

New Route to Hearing Loss Mapped

By | November 5, 2015

Deficiency in a protein called pejvakin makes inner ear cells more vulnerable to sound, unable to brace themselves against oxidative stress stimulated by noise. 

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image: Ebola’s Immune Escape

Ebola’s Immune Escape

By | November 3, 2015

The virus can persist in several tissues where the immune system is less active. Researchers are working to better understand this phenomenon and how it can stall the clearing of Ebola in survivors.

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