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tag ion channels disease medicine

A collection of images from prior stories, including illustrations of DNA, chromosomes, and various cells, microscopy images of cancer cells, and a photo of a mouse on a treadmill.
Our Favorite Cancer Stories of 2022
Dan Robitzski | Dec 27, 2022 | 4 min read
This year, cancer researchers uncovered a variety of ways that tumors can survive and spread, ranging from damaging their own DNA to exploiting the nearby microenvironment for nutrients.
Researching the Channel Change
Mike May | Aug 24, 2003 | 7 min read
Courtesy of Roderick MacKinnon, Rockefeller University Playing gatekeeper to human health, channel proteins penetrate all cell membranes. In the nervous system, armies of channels open and close in precise order to create action potentials, the brief membrane depolarizations that act as the primary form of electrical signaling in animals. These action potentials prove so enduring, functioning properly even in extreme experimental preparations, that investigators might consider ion channels in
The Breakthrough Prize ?Trophy
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
Muscle Master: Angela Dulhunty
Anna Azvolinsky | Sep 1, 2018 | 9 min read
Having pioneered the study of muscle physiology in mammals, she uncovered how ion channels enable muscle movement.
Deep Brain Optogenetic Control Without Implants
Ruth Williams | Apr 30, 2020 | 3 min read
Engineering an ultra-sensitive light-activated ion channel into brain cells allows for the control of neurons in live animals without a brain-implanted light source.
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018 | 10+ min read
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
Using Temperature-Sensitive Channels to Study Neural Circuitry
Devika G. Bansal | Nov 1, 2018 | 8 min read
Meet the researchers building a thermogenetic toolbox.
Patient-derived colon organoids from a healthy individual
Generating Mini-Guts for Drug Screening
The Scientist and MilliporeSigma | Dec 16, 2022 | 4 min read
Human gut organoids facilitate precise disease modeling and power high-throughput drug development efforts.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

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