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tag protein aggregating developmental biology

Developmental Biology
The Scientist Staff | Jun 11, 1995 | 2 min read
Edited by Neeraja Sankaran Seeding Plaques:Peter Lansbury and colleagues identified a possible mechanism for the formation of amyloid plaques in Alzheimer's disease. J.T. Jarrett, E.P. Berger, P.T. Lansbury, Jr., "The carboxy terminus of the b amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease," Biochemistry, 32:4693-7, 1993. (Cited in 53 publications through April 1995) Comments by Peter Lansbury, Jr., Massachusetts Instit
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Top 7 in developmental biology
Bob Grant | Oct 4, 2010 | 3 min read
Check out the hottest papers in developmental biology and related fields, as ranked by F1000
Photo of Ankara Jain in his lab
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
Hannah Thomasy, PhD | Oct 3, 2022 | 3 min read
The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.
Amyloid plaques on axons of neurons
The Misunderstood Proteins of Neurodegeneration
Catherine Offord | Aug 1, 2022 | 10+ min read
The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the development of disease.
Protein Purification II: Affinity Tags
Aileen Constans | Feb 17, 2002 | 9 min read
Scientists working with recombinant proteins expressed in Escherichia coli probably use at least one liquid chromatography technique to purify their protein of interest. But liquid chromatography frequently requires a considerable amount of optimization, and usually involves several different chromatographic steps to rid the sample of contaminants.1 The ideal solution would be to create a resin that is completely specific to the target protein, enabling one-step purification. Affinity chromatogr
Detecting Protein Clumps
Ruth Williams | Feb 1, 2018 | 3 min read
A synthetic genetic tool called yTRAP allows high-throughput detection of protein aggregates in cells.
 
Getting Back in Shape
Karen Zusi | Dec 1, 2015 | 3 min read
Contrary to years of research suggesting otherwise, most aggregated proteins regain their shape and functionality following heat shock.
Streamlining Membrane Protein Research with Mass Photometry
Streamlining Membrane Protein Research with Mass Photometry
The Scientist and Refeyn | Jan 24, 2023 | 3 min read
Mass photometry advances membrane protein characterization by offering fast and precise mass measurements of samples containing membrane mimetics. 
A colored microscopy image showing cells that are dying in yellow and healthy cells in blue 
Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies
Tess Joosse | Nov 14, 2022 | 2 min read
An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.

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