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image: Circadian Responses to Chemo

Circadian Responses to Chemo

By | April 21, 2015

After exposure to curcumin, rat cancer cell populations undergo a daily cycle of cell death.

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image: Insulin Interference Triggers Cancer-Linked Cachexia

Insulin Interference Triggers Cancer-Linked Cachexia

By | April 6, 2015

A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies. 

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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: My Mighty Mouse

My Mighty Mouse

By | April 1, 2015

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

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image: May the Best Rodent Win

May the Best Rodent Win

By | January 1, 2015

Are mice, considered by some to be the less intelligent rodent, edging out rats as laboratory models of decision making?

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image: Lab Versus House Mouse

Lab Versus House Mouse

By | August 21, 2014

Some behavioral traits, like female aggression, were lost with domestication, a study shows.

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image: Inflammation Data Clash

Inflammation Data Clash

By | August 7, 2014

Identical datasets yield opposite conclusions on the use of mice as models of human inflammation.

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image: Opinion: Translational Biotechnology

Opinion: Translational Biotechnology

By | February 17, 2014

Regulators must consider both the promise and potential pitfalls of new technologies when determining whether to move them into clinical trials.

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image: Common Lab Mice Differ

Common Lab Mice Differ

By | January 8, 2014

Related substrains of the Black 6 lab mouse carry key genetic polymorphisms, including one that has a dramatic effect on the rodents’ responses to cocaine.

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image: Opinion: Of Mice and Men

Opinion: Of Mice and Men

By | December 3, 2013

Researchers scramble to put mouse cancer models on solid footing.

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