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While studying a rare genetic disease, researchers discovered a signaling pathway linked to the efficiency of reprogramming somatic cells into stem cells.

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image: From Stem Cell to Oocyte In a Dish

From Stem Cell to Oocyte In a Dish

By | October 17, 2016

For the first time, scientists generate functional mouse eggs from stem cells in culture.

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image: Donor Stem Cells Improve Cardiac Function

Donor Stem Cells Improve Cardiac Function

By | October 12, 2016

After a heart attack, monkeys given induced pluripotent stem cell–derived cardiomyocytes show more regeneration in the organ, but with risks.

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image: Stem Cells Made Waves in Biology and Medicine

Stem Cells Made Waves in Biology and Medicine

By | October 1, 2016

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

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image: Thirty Years of Progress

Thirty Years of Progress

By | October 1, 2016

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

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Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.

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image: Nailing Down HAR Function

Nailing Down HAR Function

By | August 1, 2016

A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.

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image: Stem Cells for Personalized Pain Therapy Testing

Stem Cells for Personalized Pain Therapy Testing

By | April 21, 2016

Using patient-derived stem cells, researchers create laboratory neuron models that reflect a patient’s response to a pain drug.

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image: Low Mutation Rate in iPSCs

Low Mutation Rate in iPSCs

By | April 11, 2016

The mutation rate in induced pluripotent stem cells is 10 times lower than in somatic cells, scientists show.

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image: iPSCs and Cancer Risk

iPSCs and Cancer Risk

By | February 24, 2016

Reprogramming adult human cells into stem cells in vitro does not generate harmful mutations, scientists report.

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