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tag reprogramming neuroscience

Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018 | 4 min read
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Week in Review: April 28–May 2
Tracy Vence | May 2, 2014 | 3 min read
Male scientists stress mice out; using SCNT to reprogram adult cells; acetate can reach mouse brain, reduce appetite; WHO sounds “post-antibiotic era” alarm
Microscopy image showing patches of magenta and green
Three Autism-Linked Genes Converge on Tweaks to Cells’ Timing
Angie Voyles Askham, Spectrum | Feb 3, 2022 | 3 min read
The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism.
What Do New Neurons in the Brains of Adults Actually Do?
Ashley Yeager | May 1, 2020 | 10+ min read
Adult neurogenesis, already appreciated for its role in learning and memory, also participates in mental health and possibly even attention, new research suggests.
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
The Four R's
Amy Norton | Nov 21, 2004 | 7 min read
Teams at each of New York City's leading universities are making important research advances.
A Paradigm Shift in Stem Cell Research?
Ricki Lewis | Mar 5, 2000 | 9 min read
Photo: E.D. Laywell, UT MemphisMultipotent clones of cells derived from the adult human brain With the promises and challenges of stem cell research in the headlines, visions of artificial livers dance in the public's eye. Bioethicists, politicians, and citizens alike continue to debate whether public funds should be used to obtain cells from human embryos and fetuses. On the scientific front, however, the implications of stem cell research are even more profound than offering replacement parts.
Ten Technologies in Five Years
Sam Jaffe(sjaffe@the-scientist.com) | Dec 5, 2004 | 8 min read
When scientists make long-term research plans, they must try to anticipate how emerging technologies will influence their work in the coming years.

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