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tag synapse formation cell molecular biology

The image shows two adult prairie voles. The voles have a brown coat and are touching each other’s snouts.
Molecular Signatures of a Broken Heart
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 3 min read
The transcriptional profiles in the brains of prairie voles changed after a long breakup, revealing a molecular shift that might help them cope with the loss of a partner.
Dissecting the Immunological Synapse
Josh Roberts | May 4, 2003 | 7 min read
Courtesy of Michael Dustin PASS IT ON: A T cell (blue) interacts with a dendritic cell (yellow) through a molecular pattern described as an immunological synapse (red = adhesion, green = foreign antigen). This is a composite image of a scanning electron micrograph and a fluorescence image. We can do things that haven't been done before, I think, ever in cell biology," exclaims Mark Davis of Stanford University. His 3-D, fluorescence video-microscopy system allows him to count the number
black-and-white brain scan showing tumor
Glioblastoma Cells Imitate Immature Neurons to Invade the Brain
Sophie Fessl, PhD | Aug 5, 2022 | 3 min read
Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.
Can Single Cells Learn?
Catherine Offord | May 1, 2021 | 10+ min read
A controversial idea from the mid-20th century is attracting renewed attention from researchers developing theories for how cognition arises with or without a brain.
Critical Connections
Karen Hopkin | Dec 1, 2011 | 9 min read
Through a series of sustained collaborations, Joshua Sanes has deciphered the molecular synergy that guides synapse formation.
Sleep adjusts fly synapses
Bob Grant | Apr 1, 2009 | 3 min read
New findings support a controversial hypothesis about the biological role of sleep: Snoozing may be a way for the brain to clear clutter accumulated after a hard day of synapse forming and strengthening. Two __Science__ studies published today suggest that the brains of sleeping __Drosophila__ undergo an overall depression in synaptic strength and number, eliminating some minor neuronal connections while merely weakening stronger ones.Expression of synaptic markers is low aftersleep (left) and h
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Certain Glial Cells Appear to Help Prevent Muscle Fatigue
Ashley Yeager | May 1, 2018 | 3 min read
The flow of calcium and potassium ions keeps muscles contracting in the diaphragms of neonatal mice, but if a key protein receptor is missing, fatigue sets in more quickly.
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.

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