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image: Screening  with CRISPR

Screening with CRISPR

By | June 1, 2016

Ever-improving CRISPR-based tools are already ripe for large-scale genetic screens.

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image: The Fatty Acid–Ketone Switch

The Fatty Acid–Ketone Switch

By | June 1, 2016

In failing hearts, cardiomyocytes change their fuel preference.

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Member, Department of Immunology, St. Jude Children’s Research Hospital. Age: 43

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image: Noncoding RNAs Not So Noncoding

Noncoding RNAs Not So Noncoding

By | June 1, 2016

Bits of the transcriptome once believed to function as RNA molecules are in fact translated into small proteins.

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image: Synthetic Biology Comes into Its Own

Synthetic Biology Comes into Its Own

By | June 1, 2016

Researchers create novel genetic circuits that give insight into, and are inspired by, nature.

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image: In Failing Hearts, Cardiomyocytes Alter Metabolism

In Failing Hearts, Cardiomyocytes Alter Metabolism

By | June 1, 2016

While the heart cells normally burn fatty acids, when things go wrong ketones become the preferred fuel source.

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image: Toward Targeted Therapies for Autoimmune Disorders

Toward Targeted Therapies for Autoimmune Disorders

By | June 1, 2016

Training the immune system to cease fire on native tissues could improve outcomes for autoimmune patients, but clinical progress has been slow.

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image: Editing Genomes to Record Cellular Histories

Editing Genomes to Record Cellular Histories

By | May 26, 2016

Researchers harness the power of genome editing to track cell lineages throughout zebrafish development.

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image: FDA Approves Bladder Cancer Immunotherapy

FDA Approves Bladder Cancer Immunotherapy

By | May 23, 2016

The US Food and Drug Administration greenlights Roche’s Tecentriq, which blocks a protein that obstructs the immune system’s ability to fight cancer.

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Certain drugs could worsen graft-versus-host disease in stem cell transplant patients, scientists show.

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