Jack Lucentini | Sep 7, 2003 | 7 min read
© 2002 Wiley Periodicals, Inc. AT DEATH'S DOOR: Negatively stained Pseu-domonas aeruginosa (A) untreated, (B) treated with amphipathic a helical lytic peptide dia-stereomer (containing both L- and D-amino acids), and (C) treated with with the all L-amino acid peptide. All were treated at 60% of their minimal inhibitory concentration (MIC). At or above the MIC, significant lysis occurs (not shown). (Y. Shai, "Mode of action of membrane active antimicrobial peptides," Biopolymers (Petp