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image: Similarities and Differences

Similarities and Differences

By | November 21, 2014

Results from the Mouse ENCODE project point to key divergences in gene regulation architecture compared to humans.


image: How a Memory Is Made

How a Memory Is Made

By | November 13, 2014

Transcription factor levels dictate which neurons in a network store a memory.

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image: Enhanced Enhancers

Enhanced Enhancers

By | November 1, 2014

The recent discovery of super-enhancers may offer new drug targets for a range of diseases.


image: Poor Little Devils

Poor Little Devils

By | November 1, 2014

See the devastating infectious cancer that may drive the Tasmanian Devil to extinction.


image: Epigenetics of Trained Innate Immunity

Epigenetics of Trained Innate Immunity

By | September 25, 2014

Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages.


image: Done with Immunosuppressants

Done with Immunosuppressants

By | July 3, 2014

Adult sickle-cell patients have safely stopped taking their immunosuppressant medication thanks to a new type of blood stem-cell transplant.


image: Protein Clumps Spread Inflammation

Protein Clumps Spread Inflammation

By | June 22, 2014

ASC specks—protein aggregations that drive inflammation—are released from dying immune cells, expanding the reach of a defense response.

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image: Ancient Apoptosis

Ancient Apoptosis

By | June 9, 2014

Humans and coral share a cell-death pathway that has been conserved between them for more than half a billion years.


image: Week in Review: June 2–6

Week in Review: June 2–6

By | June 6, 2014

The malnourished microbiome; innate immunity and beige fat; tools for stem cell self-renewal; predicting tomorrow’s PIs; MERS update


image: Minimal Toolkit for Stem Cell Self-Renewal

Minimal Toolkit for Stem Cell Self-Renewal

By | June 5, 2014

Researchers identify a network of a dozen transcription factors needed to maintain the pluripotent state of mouse embryonic stem cells. 


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