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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Benefits of Missing MYC

Benefits of Missing MYC

By | January 22, 2015

Mice engineered to have just one copy of the gene Myc live longer, healthier lives than wild-type animals.

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image: Fertility Treatment Fallout

Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

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image: Toward Lab-Grown Gametes

Toward Lab-Grown Gametes

By | December 30, 2014

From stem cells, scientists generate early egg- and sperm-like cells in vitro.

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image: NIH Study Canceled

NIH Study Canceled

By | December 15, 2014

The National Institutes of Health shutters its initiative to track the health of 100,000 children through adulthood.

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image: Similarities and Differences

Similarities and Differences

By | November 21, 2014

Results from the Mouse ENCODE project point to key divergences in gene regulation architecture compared to humans.

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image: Mother’s Microbes Protect Baby’s Brain

Mother’s Microbes Protect Baby’s Brain

By | November 19, 2014

Bacteria in the gut of a pregnant mouse strengthen the blood-brain barrier of her developing fetus.

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image: How a Memory Is Made

How a Memory Is Made

By | November 13, 2014

Transcription factor levels dictate which neurons in a network store a memory.

1 Comment

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