proteomics

Researchers initially set out to investigate the relationship between copper homeostasis and the rare Menkes disease, but they also found links to Parkinson’s.

Researchers are looking to proteins to explore the biology of ancient organisms, from medieval humans all the way back to dinosaurs.

How to analyze ancient proteins

Researchers are using souped-up mass spectrometry to localize proteins within brain cells.

From single-cell analysis to whole-genome sequencing, this year's best new products shine on many levels.

Transcript abundance isn’t a reliable indicator of protein quantity, contrary to studies’ suggestions. 

The unicellular ancestor of animals may have harbored some of the molecular tools that its many-celled descendants use to coordinate and direct cell differentiation and function, scientists show.

Using proteomics methods to inform antigen selection

Cell type–specific proteomic analyses are now possible from paraffin-embedded tissues.

Overwintering ground squirrels survive fluctuations in body temperature that would cause cardiac arrest in nonhibernators.

Visit the lab of Matthew Andrews at the University of Minnesota Duluth, who studies hibernating thirteen-lined ground squirrels to learn how their hearts manage extreme temperature fluctuations.

Using mass spec to study protein-protein interactions

Researchers create cerebral organoids using induced pluripotent stem cells from patient skin cells and characterize protein-expression changes linked to cognitive impairment.