medicine, immunology

Researchers find that bacteria stimulate a headache-causing pain pathway to suppress the immune system and infect the brain. 

A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.

Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.

Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.

Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.

By engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.

The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice. 

A clinical trial finds that the anticoagulant apixaban, which has been prescribed to help COVID-19 patients recover, is ineffective and in rare instances dangerous.

Researchers find signatures pre- and post-vaccination that correlate with a more robust immune response. 

King Charles III has a long history of promoting homeopathic or alternative medical treatments not supported by scientific evidence.

The results from two large clinical trials don't support the idea that supplements of the vitamin bolster immune defenses against SARS-CoV-2.

Evidence thus far shows that pregnant people infected with SARS-CoV-2 are at higher risk for severe disease and death, as well as complications in their pregnancies.

The newly authorized intradermal vaccination only requires one-fifth of the usual vaccine dose. This will help stretch out the limited vaccine supply, experts say, but only if healthcare personnel receive sufficient training.

Use of the drugs in children under the age of two was associated with lower antibody levels after the jabs—perhaps, researchers suggest, due to microbiome alterations.

A new study reveals that the fibroblasts in tissue surrounding acne infections play an active role in the body’s immune response—and that existing treatments help trigger them to do so.

Umbilical cord blood may be a good alternative to bone marrow transplants for treating HIV in patients with HIV and cancer.

First, the genetically engineered cells became CD8⁺ killer T cells that wiped out his leukemia. Then they transformed into a stable population of CD4⁺ helper T cells that continue to circulate in his body.

Early reports that Omicron causes less-severe disease than Delta seem to be borne out, but it’s not yet clear to what extent that’s due to the variant itself versus the populations it’s infecting.

Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.