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image: CRISPR–Enabled Epigenome Editing

CRISPR–Enabled Epigenome Editing

By | April 6, 2015

Researchers apply the genome-editing technology to alter histones at distant gene enhancers, controlling gene expression.

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image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: Capsule Reviews

Capsule Reviews

By | April 1, 2015

Junk DNA, Cuckoo, Sapiens, and Cool

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image: Getting Your Sugar Fix

Getting Your Sugar Fix

By | April 1, 2015

A guide to glycan microarrays

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: Soil Bacteria Live on Wine Grapes

Soil Bacteria Live on Wine Grapes

By | March 25, 2015

The earthiness of Merlot may have to do with grapevine-dwelling microbiota.

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image: Quorum-Sensing Molecule Modifies Gut Microbiota

Quorum-Sensing Molecule Modifies Gut Microbiota

By | March 19, 2015

Increasing the abundance of a chemical some microbes use to communicate with one another can help reinstate beneficial bacterial populations in the guts of antibiotic-treated mice. 

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