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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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“Ultimate DISCO” uses a solvent that shrinks whole animals and preserves fluorescence for months.

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Disrupting the light/dark cycles of pregnant mice, researchers observe detrimental effects in the mouths of the animals’ pups.

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image: Student Alleges His Team Didn’t Earn CRISPR Patent

Student Alleges His Team Didn’t Earn CRISPR Patent

By | August 18, 2016

A former researcher at the Broad Institute has suggested the University of California, Berkeley, team deserves credit for inventing the gene-editing technique.

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Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

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image: Antibiotic Resistance Reaches Brazil

Antibiotic Resistance Reaches Brazil

By | August 8, 2016

Scientists detect a colistin-resistance gene in a clinical sample.

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image: Fecal Transplant Pill Fails Trial

Fecal Transplant Pill Fails Trial

By | August 1, 2016

Seres Therapeutics’s microbiome-targeting therapy for recurrent Clostridium difficile infection fails a Phase 2 clinical trial.

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From sequencing bacteriophages to synthesizing bacterial genomes to defining a minimal genome

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image: Cullen Buie Parses Pathogens With Passion

Cullen Buie Parses Pathogens With Passion

By | August 1, 2016

Associate Professor, Department of Mechanical Engineering, MIT. Age: 34

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