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image: OPSINS: Tools of the trade

OPSINS: Tools of the trade

By | July 1, 2011

The optogenetic toolset is composed of genetically encoded molecules that, when targeted to specific neurons in the brain, enable the electrical activity of those neurons to be driven or silenced by light. When these opsins are expressed in the lipid

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image: A Scar Nobly Got

A Scar Nobly Got

By | July 1, 2011

The story of the US government’s efforts to stamp out smallpox in the early 20th century offers insights into the science and practice of mass vaccination.

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image: Capsule Reviews

Capsule Reviews

By | July 1, 2011

Solar, The Dark X, The Sky's Dark Labyrinth, Spiral

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image: The Ninefold Ring

The Ninefold Ring

By | July 1, 2011

Editor’s Choice in Structural Biology

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image: Book excerpt from <em>Pox: An American History</em>

Book excerpt from Pox: An American History

By | July 1, 2011

In Chapter 5, "The Stable and the Laboratory," author Michael Willrich explores the burgeoning vaccine manufacture industry that ramped up to combat smallpox epidemics in turn-of-the-twentieth-century American cities.

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image: Desperately Seeking Radioisotopes

Desperately Seeking Radioisotopes

By | July 1, 2011

New strategies are needed to address the current and future shortages of radioisotopes that threaten medical research and treatment.

21 Comments

image: Meet the Crystal Smasher

Meet the Crystal Smasher

By | July 1, 2011

Take a tour of the Linac Coherent Light Source (LCLS), whose ultra-powerful X-ray beam is being used to solve the structures of proteins that are notoriously hard to crystallize.

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image: Optogenetics: A Light Switch for Neurons

Optogenetics: A Light Switch for Neurons

By | July 1, 2011

This animation illustrates optogenetics—a radical new technology for controlling brain activity with light. Ed Boyden, the co-inventor of this technology, is a professor at the MIT Media Lab and at the McGovern Institute for Brain Research, where he continues to develop new technologies for controlling brain activity.

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image: Scientist to Watch

Scientist to Watch

By | July 1, 2011

“This is my trophy,” says biologist Michael Edidin, walking across his office at Johns Hopkins University to pick up two oversized clock hands, once part of the stately clock tower that still stands on the Baltimore campus. In his right-hand pocket i

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image: Smashing Crystals

Smashing Crystals

By | July 1, 2011

A powerful new X-ray–generating laser is imaging smaller crystals than ever before.

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