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image: CRISPR–Enabled Epigenome Editing

CRISPR–Enabled Epigenome Editing

By | April 6, 2015

Researchers apply the genome-editing technology to alter histones at distant gene enhancers, controlling gene expression.

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image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: Cancer Immunotherapist

Cancer Immunotherapist

By | April 1, 2015

Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.

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image: Cancer Kismet

Cancer Kismet

By | April 1, 2015

Fate mapping allows researchers to follow cancer progression from its cell type of origin.

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image: Capsule Reviews

Capsule Reviews

By | April 1, 2015

Junk DNA, Cuckoo, Sapiens, and Cool

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: Getting Your Sugar Fix

Getting Your Sugar Fix

By | April 1, 2015

A guide to glycan microarrays

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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