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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Protein or Perish

Protein or Perish

By | September 1, 2016

A bacteriophage must evolve certain variants of a protein or die.

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image: Popular Tumor Cell Line Contaminated

Popular Tumor Cell Line Contaminated

By | August 31, 2016

A commercially available glioblastoma cell line appears to be from a different source than its stated origins.

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image: That Other CRISPR Patent Dispute

That Other CRISPR Patent Dispute

By | August 31, 2016

The Broad Institute and Rockefeller University disagree over which scientists should be named as inventors on certain patents involving the gene-editing technology.

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image: Dogs Respond to Words and Inflection

Dogs Respond to Words and Inflection

By | August 31, 2016

Using an MRI scanner to examine how dogs’ brains process speech, researchers find that our canine companions hear both what we say and how we say it. 

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“Ultimate DISCO” uses a solvent that shrinks whole animals and preserves fluorescence for months.

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Disrupting the light/dark cycles of pregnant mice, researchers observe detrimental effects in the mouths of the animals’ pups.

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image: Student Alleges His Team Didn’t Earn CRISPR Patent

Student Alleges His Team Didn’t Earn CRISPR Patent

By | August 18, 2016

A former researcher at the Broad Institute has suggested the University of California, Berkeley, team deserves credit for inventing the gene-editing technique.

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Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

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image: Stimulating Novel Neural Circuits in the Mouse Brain

Stimulating Novel Neural Circuits in the Mouse Brain

By | August 11, 2016

With light, researchers can coax a group of neurons in the visual cortices of living mice to fire in concert.

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