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image: Toggling CRISPR Activity with a Chemical Switch

Toggling CRISPR Activity with a Chemical Switch

By | September 12, 2016

Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.

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image: Week in Review: September 5–9

Week in Review: September 5–9

By | September 9, 2016

Environmental magnetite in the human brain; prion structure takes shape; watching E. coli evolve in real time; learning from others’ behavior 

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image: Giant Petri Dish Displays Evolution in Space and Time

Giant Petri Dish Displays Evolution in Space and Time

By | September 8, 2016

As E. coli bacteria spread over increasingly concentrated antibiotics, researchers discover novel evolutionary pathways that confer resistance.

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image: Group Proposes Strategies to Improve Antibodies

Group Proposes Strategies to Improve Antibodies

By | September 5, 2016

An expert committee encourages reagent providers to adopt one of five methods to validate products.

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image: The History of Optogenetics Revised

The History of Optogenetics Revised

By | September 1, 2016

Credit for the neuroscience technique has largely overlooked the researcher who first demonstrated the method.

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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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image: Promoting Protein Partnerships

Promoting Protein Partnerships

By | September 1, 2016

Scientists generate new protein-protein interactions at an impressive PACE.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Odor, Taste, and Light Receptors in Unusual Locations

Odor, Taste, and Light Receptors in Unusual Locations

By | September 1, 2016

From the gut and airways to the blood, muscle, and skin, diverse sensory receptors are doing unconventional things.

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image: Proprioception: The Sense Within

Proprioception: The Sense Within

By and | September 1, 2016

Knowing where our bodies are in space is critical for the control of our movements and for our sense of self.

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