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tag techniques genetics genomics ecology neuroscience disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
artistic representation of jumping gene
Jumping Genes Can Cause Movement Disorder: Study
Sophie Fessl, PhD | Sep 13, 2022 | 3 min read
Mice with overactive LINE-1 retrotransposons in their brains exhibit movement difficulties, suggesting the genetic elements may play a role in ataxia in humans. 
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

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