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image: Targeting the Noncoding Genome with CRISPR

Targeting the Noncoding Genome with CRISPR

By | September 29, 2016

Two independent groups demonstrate the utility of CRISPR-based techniques to identify regulatory elements that govern disease-linked genes. 

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image: Geography of Genetic Diversity

Geography of Genetic Diversity

By | September 29, 2016

Mammals and amphibians show greater intraspecific genetic diversity in the tropics compared with temperate regions.

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image: “Out of Africa” Theory Gets the Genomic Treatment

“Out of Africa” Theory Gets the Genomic Treatment

By | September 26, 2016

A trio of genetic studies on seldom-studied indigenous populations points to a single wave of migration as humanity wandered from its evolutionary homeland into the rest of the world.

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image: Toggling CRISPR Activity with a Chemical Switch

Toggling CRISPR Activity with a Chemical Switch

By | September 12, 2016

Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.

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image: Week in Review: September 5–9

Week in Review: September 5–9

By | September 9, 2016

Environmental magnetite in the human brain; prion structure takes shape; watching E. coli evolve in real time; learning from others’ behavior 

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Ancestries of nearly two dozen indigenous groups in the region reveal a close link between the genetic clustering of populations and the Kalahari Desert’s ecogeography.

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image: Zika Update

Zika Update

By | September 7, 2016

Virus’s genome to aid in diagnoses; bees caught in crossfire of mosquito sprays; Zika spreads in Asia; US Congress revisits Zika funding

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image: Group Proposes Strategies to Improve Antibodies

Group Proposes Strategies to Improve Antibodies

By | September 5, 2016

An expert committee encourages reagent providers to adopt one of five methods to validate products.

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image: The History of Optogenetics Revised

The History of Optogenetics Revised

By | September 1, 2016

Credit for the neuroscience technique has largely overlooked the researcher who first demonstrated the method.

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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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