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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.

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image: Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case

By | February 15, 2017

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

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image: Deep Pocket Exploration

Deep Pocket Exploration

By | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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image: Discovering Novel Antibiotics

Discovering Novel Antibiotics

By | February 1, 2017

Three methods identify and activate silent bacterial gene clusters to uncover new drugs

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image: Infographic: Modeling Molecules’ Receptor Binding

Infographic: Modeling Molecules’ Receptor Binding

By | February 1, 2017

A software upgrade follows ligands step-wise into their binding sites on receptors.

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image: Characterizing the Imprintome

Characterizing the Imprintome

By | January 1, 2017

Three techniques for identifying the collection of maternal and paternal genes silenced in offspring

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Top Technical Advances 2016

Top Technical Advances 2016

By | December 15, 2016

The year’s most impressive achievements include methods to watch translation in cells, trace cell fates, avoid mitochondrial mutations, edit DNA, and build antibiotics from scratch.

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image: How to Track Cell Lineages As They Develop

How to Track Cell Lineages As They Develop

By | December 1, 2016

Sequencing and gene-editing advances make tracing a cells journey throughout development easier than ever.

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