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Ribbon diagram of the protein coat of an adeno-associated virus
Preprints Propose Constellation of Causes for Kids’ Liver Disease
Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.
Preprints Propose Constellation of Causes for Kids’ Liver Disease
Preprints Propose Constellation of Causes for Kids’ Liver Disease

Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.

Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.

epidemiology, disease & medicine, microbiology

mis-c multisystem inflammatory syndrome in children covid-19 coronavirus pandemic sars-cov-2 antibody cardiac inflammation icu intensive care kids infection vomiting abdominal pain diarrhea fever
Most Kids with MIS-C Report Few or No COVID-19 Symptoms: Study
Kerry Grens | Apr 7, 2021 | 2 min read
A review of hundreds of cases finds that only a minority of patients noted being sick with a coronavirus infection prior to developing the severe inflammatory condition.
SARS-CoV-2 Genetic Variant May Be More Transmissible
Abby Olena, PhD | Nov 25, 2020 | 4 min read
The so-called 614G mutation in the viral spike protein does not appear to cause more severe cases of COVID-19, but multiple studies indicate that it could be more contagious.
adam kucharski the rules of contagion
Connecting the DOTS
Adam Kucharski | Aug 18, 2020 | 3 min read
The four factors that drive contagion
Disrupted Habitats Have More Zoonotic Disease Hosts: Study
Lisa Winter | Aug 6, 2020 | 2 min read
Animals that can host pathogens dangerous to humans, such as rodents, birds, and bats, are proportionately more common in human-occupied spaces than in remote areas.
Infographic: What We Know About How Masks Can Slow Disease Spread
Diana Kwon | Jul 8, 2020 | 1 min read
Not all masks are created equal, and how they are worn makes a difference too.
Counting the Lives Saved by Lockdowns—and Lost to Slow Action
David Adam | Jul 6, 2020 | 4 min read
Social distancing measures prevented millions of COVID-19–related deaths around the world, according to a handful of studies, but it’s hard to quantify the effects with certainty.
Special Report
Surgisphere Sows Confusion About Another Unproven COVID-19 Drug
Catherine Offord | Jun 16, 2020 | 10+ min read
The company behind a now-discredited study on hydroxychloroquine also posted a report that has been cited by Latin American governments recommending ivermectin as a possible coronavirus treatment. Clinicians there say the effects have been extremely damaging.
gold spots on a blue background
A Brief History of Human Coronaviruses
Shawna Williams | Jun 2, 2020 | 5 min read
Milder, cold-causing members of this pathogenic viral family long remained under the radar, although they aren’t entirely harmless.
Exclusive
Disputed Hydroxychloroquine Study Brings Scrutiny to Surgisphere
Catherine Offord | May 30, 2020 | 9 min read
Scientists have raised questions about the dataset published in The Lancet last week that triggered the suspension of clinical trials around the world—and about Surgisphere Corporation, the company behind the study.
UK Launches Trial of Contact Tracing App on Isle of Wight
Jef Akst | May 6, 2020 | 2 min read
Bluetooth-enabled technology will attempt to track people’s interactions on the British island—and potentially elsewhere in the UK—as lockdowns are lifted.
special report
How (Not) to Do an Antibody Survey for SARS-CoV-2
Catherine Offord | Apr 28, 2020 | 10+ min read
Preprints from the first round of seroprevalence studies indicate that many more people have been infected with the virus than previously reported. Some of these studies also have serious design flaws.
First US COVID-19 Deaths Happened Weeks Earlier than Thought
Catherine Offord | Apr 22, 2020 | 2 min read
Autopsies recently carried out in California show that one person died of the disease on February 6—three weeks before the nation recorded its first fatality.
coronavirus covid-19 sars-cov-2 modeling predictions projections when it will peak pandemic
Modelers Struggle to Predict the Future of the COVID-19 Pandemic
David Adam | Mar 12, 2020 | 5 min read
Disease experts have largely focused on how we got to where we are now with coronavirus infections. Improved data collection and sharing can enhance projections of what’s to come.
a person washing their hands
Studies Estimate Incubation Time, Infectious Period of SARS-CoV-2
Shawna Williams | Mar 10, 2020 | 2 min read
It takes a median of five days after infection to get sick, and patients shed the most coronavirus particles early in the illness, according to two new reports.
Watch the Spread of COVID-19
Catherine Offord | Mar 5, 2020 | 2 min read
Our maps and charts, updated regularly, offer a striking view of the global move of the novel coronavirus.
Flu and HIV Drugs Show Efficacy Against Coronavirus
Catherine Offord | Feb 3, 2020 | 2 min read
Combining the medications improved conditions in patients with severe 2019-nCoV infections, say doctors in Thailand.
Going Viral for the Wrong Reasons
Bob Grant | Jan 30, 2020 | 3 min read
What is a publication to do when readers misuse its content?
Enterovirus Might Be Behind Kids’ Paralysis: Preprint
Catherine Offord | Jun 17, 2019 | 2 min read
Researchers identify a possible driver of acute flaccid myelitis, a polio-like disease diagnosed in more than 500 children over the last few years.
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