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tag manipulation disease medicine culture

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Bacteria on the skin
Biotech Tries Manipulating the Skin Microbiome
Bianca Nogrady | Apr 18, 2022 | 8 min read
Researchers are revealing the complexity of the microbial community living on the body—and paving the way for new bacteria-targeting treatments for acne and other dermatological conditions.
Opinion: Celebrities Pushing Drugs?
Howard Brody | Jan 30, 2012 | 4 min read
Celebrity spokespeople for pharma companies can manipulate the public’s understanding of disease.
How Manipulating Rodent Memories Can Elucidate Neurological Function
Amber Dance | May 1, 2020 | 10+ min read
Strategies to make lab animals forget, remember, or experience false recollections probe how memory works, and may inspire treatments for neurological diseases.
Image of pancreatic organoids under a microscope with immunofluorescent staining
Pancreatic Organoids Take the Stage
Laura Tran, PhD | Dec 1, 2023 | 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.
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Time Traveling Mini-Brains on a Mission to Conquer Space
Iris Kulbatski, PhD | Jun 1, 2023 | 5 min read
Alysson Muotri launched brain organoids into outer space and found that microgravity enriches our understanding of brain development and disease.
Is Medicine Ready for Clinical CRISPR?
John Parrington | Dec 1, 2016 | 3 min read
Using precision genome editing to treat or prevent human disease may require several leaps of faith.

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