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tag chronic pain neuroscience immunology cell molecular biology

Resolving Chronic Pain
Claudia Sommer and Frank Birklein | Jan 1, 2012 | 10+ min read
The body’s own mechanism for dispersing the inflammatory reaction might lead to new treatments for chronic pain.
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez, PhD | May 12, 2022 | 3 min read
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
Sex Differences in Pain Pathway
Amanda B. Keener | Jun 29, 2015 | 4 min read
Male and female mice utilize different immune cells to process pain, a study shows.
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018 | 10 min read
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Photograph of a mouse covering his face with his paw.
Bless You: Mouse Model Reveals Molecular Pathway Behind Sneezing
Amanda Heidt | Oct 1, 2021 | 3 min read
Researchers have identified specific cells and neuropeptides involved in mediating the sneeze response in mice exposed to allergens or chemical irritants such as capsaicin.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
Getting at the Molecular Roots of Pain
Karen Hopkin | Jan 3, 1999 | 8 min read
to eliminate difficult-to-control pain while leaving normal sensation intact. Pain is a part of life. Often, a few painkillers and some rest are enough to soothe the scraped knees of childhood and the aches and sprains of adulthood. But for some, pain is not as fleeting or as easily dismissed. The pain from cancer, chemotherapy, arthritis, AIDS, and other diseases can be unrelenting and incapacitating. Some individuals even experience constant, bone-crushing pain for no apparent reason. For man
Top 7 immunology papers
Edyta Zielinska | Aug 23, 2010 | 3 min read
#1 T cell debate solved Mature T cells in the thymus are attracted to a molecule expressed by cells covering blood vessels, resolving a long standing puzzle of how cells escape into the body to fight infections. linkurl:(See our news story here.);http://www.the-scientist.com/blog/display/57375/ M.A. Zachariah, J.G. Cyster, "Neural crest-derived pericytes promote egress of mature thymocytes at the corticomedullary junction," linkurl:__Science,__;http://www.ncbi.nlm.nih.gov/sites/entrez/2041345
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018 | 10+ min read
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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