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tag chronic pain cell molecular biology evolution

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez, PhD | May 12, 2022 | 3 min read
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
Metabolites Involved in Chronic Pain
Jeffrey M. Perkel | Jan 22, 2012 | 3 min read
Untargeted metabolic profiling implicates a new suite of metabolites that may be involved in nerve damage-induced pain.
Natural Opioids Linked to Chronic Pain
Jef Akst | Sep 19, 2013 | 4 min read
The body’s own pain-quelling system may be at the root of chronic pain and symptoms of opioid withdrawal, according to a new study in mice.
red ants coming out of dirt hole
Bull Ant Venom Evolved to Make Bites More Painful to Mammals
Dan Robitzski | Jul 5, 2022 | 2 min read
A peptide found in bull ant venom closely resembles a hormone of its primary predator, triggering hypersensitivity and making subsequent bites even more painful than the ones that came before.
How Evolution Made the Highveld Mole Rat Impervious to Ant Stings
Shawna Williams | Sep 1, 2019 | 5 min read
Researchers identify changes to a pain receptor and to an ion channel that appear to enable the rodents to colonize otherwise inhospitable burrows.
Getting at the Molecular Roots of Pain
Karen Hopkin | Jan 3, 1999 | 8 min read
to eliminate difficult-to-control pain while leaving normal sensation intact. Pain is a part of life. Often, a few painkillers and some rest are enough to soothe the scraped knees of childhood and the aches and sprains of adulthood. But for some, pain is not as fleeting or as easily dismissed. The pain from cancer, chemotherapy, arthritis, AIDS, and other diseases can be unrelenting and incapacitating. Some individuals even experience constant, bone-crushing pain for no apparent reason. For man
Molecular Blueprints
Cristina Luiggi | Mar 27, 2012 | 3 min read
Check out the latest crop of high-resolution structures and how they inform biological function.

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