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tag chronic pain evolution genetics genomics disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
Scientific Medicine and Chronic Fatigue Syndrome
Mary Mcnamara | Nov 12, 2000 | 6 min read
Illustration: A. Canamucio There has never been a better time, technologically, for our federal health agencies to launch a significant effort to prevent and control a chronic disease that has inflicted suffering on mankind for centuries. Chronic fatigue syndrome (CFS) is the current name for an illness with many names and a long history. In 1681 Thomas Sydenham, founder of modern clinical, scientific, and public health medicine, described a disease spectrum identical to it called "muscular rheu
A Geneticist’s Quest to Understand His Son’s Mysterious Disease
Tracie White | Jan 1, 2021 | 4 min read
Ronald Davis of Stanford University changed his focus to research on ME/CFS, the disease formerly known as chronic fatigue syndrome, in a bid to help his son and others like him.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Plague Genome: The Evolution Of a Pathogen
Ricki Lewis | Oct 28, 2001 | 7 min read
Plague has earned a place in history books as the Black Death of medieval Europe, and in novels, from Albert Camus' classic The Plague, to the more recent Year of Wonders.1,2 A different medium for telling the tale of the plague bacterium Yersinia pestis is its genome, recently sequenced by researchers at the Sanger Centre, the London School of Hygiene and Tropical Medicine, the Royal London School of Medicine and Dentistry, and the Imperial College of Science, Technology and Medicine.3 In addi
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
an illustration of a woman holding her head
Could COVID-19 Trigger Chronic Disease in Some People?
Katarina Zimmer | Jul 17, 2020 | 8 min read
A handful of viruses have been associated with long-term, debilitating symptoms in a subset of those who become infected. Early signs hint that SARS-CoV-2 may do the same.
Advanced Spatial Tools Map Hematopoietic Stem Cell Niches
Niki Spahich, PhD | Jan 15, 2024 | 4 min read
New technologies and archival tissue biopsy samples enable exploration of changes in the bone marrow as people age.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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