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image: Stem Cell Suicide Switch

Stem Cell Suicide Switch

By | May 3, 2012

Human embryonic stem cells swiftly kill themselves in response to DNA damage.

10 Comments

image: The Sugar Lnc

The Sugar Lnc

By | May 1, 2012

Genes that react to cellular sugar content are regulated by a long non-coding RNA via an unexpected mechanism

2 Comments

image: Boyle’s Monsters, 1665

Boyle’s Monsters, 1665

By | May 1, 2012

From accounts of deformed animals to scratch-and-sniff technology, Robert Boyle's early contributions to the Royal Society of London were prolific and wide ranging.

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image: The Two Faces of Metastasis

The Two Faces of Metastasis

By | April 1, 2012

During development, the cells of an embryo change their pattern of gene expression, which allows them to detach from their original location and migrate to another part of the embryo, where the pattern changes again to allow formation of a new organ.

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image: Are Cancer Stem Cells Ready for Prime Time?

Are Cancer Stem Cells Ready for Prime Time?

By | April 1, 2012

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.

48 Comments

image: What it Takes to Develop Better Drugs for Kids

What it Takes to Develop Better Drugs for Kids

By | March 1, 2012

Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials.  

2 Comments

image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve

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image: How to Make Eyeball Stew

How to Make Eyeball Stew

By | March 1, 2012

Editor's choice in developmental biology

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image: Child-Proofing Drugs

Child-Proofing Drugs

By | March 1, 2012

When children need medications, getting the dosing and method of administration right is like trying to hit a moving target with an untried weapon.

6 Comments

image: Model Citizen

Model Citizen

By | March 1, 2012

With an eye to understanding animal regeneration, Alejandro Sánchez Alvarado has turned a freshwater planarian into a model system to watch.

2 Comments

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