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image: On the Chain Gang

On the Chain Gang

By | July 1, 2012

More than simply helping haul out a cell’s garbage, ubiquitin, with its panoply of chain lengths and shapes, marks and regulates many unrelated cellular processes.

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image: Ubiquitin basics

Ubiquitin basics

By | July 1, 2012

Despite its discovery as a protein that seems to show up everywhere, at least in eukaryotic cells, researchers are only beginning to scratch the surface of all of the cellular functions involving ubiquitin. 

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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image: Freezing Time

Freezing Time

By | May 1, 2012

Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.

15 Comments

image: Molecular Blueprints

Molecular Blueprints

By | March 27, 2012

Check out the latest crop of high-resolution structures and how they inform biological function.

2 Comments

image: David Sabatini: Demystifying mTOR

David Sabatini: Demystifying mTOR

By | March 1, 2012

Principal Investigator, Whitehead Institute for Biomedical Research. Associate Professor, Department of Biology, Massachusetts Institute of Technology. Age: 44

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image: Promoting Death

Promoting Death

By | March 1, 2012

Editor's choice in biochemistry

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image: Shielding Cancer Cells from Damage

Shielding Cancer Cells from Damage

By | November 4, 2011

An alternative form of an enzyme involved in the glucose metabolism pathway protects cancer cells from oxidative stress.

12 Comments

image: BRCA1 Further Elucidated

BRCA1 Further Elucidated

By | October 27, 2011

Researchers have pinpointed the region of a key cancer gene that’s involved in tumor suppression.

9 Comments

image: Top 7 in Biochemistry

Top 7 in Biochemistry

By | October 24, 2011

A snapshot of the most highly ranked articles in biochemistry and related areas, from Faculty of 1000

3 Comments

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