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» mouse research and immunology

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image: Inflammation Overdrive

Inflammation Overdrive

By | January 15, 2015

Experimental vaccines that specifically boost T helper cells lead to immunopathology and death in mice.

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image: X Inactivation Discoverer Dies

X Inactivation Discoverer Dies

By | January 9, 2015

British geneticist Mary Lyon has passed away at age 89.

1 Comment

image: Fat to the Rescue

Fat to the Rescue

By | January 5, 2015

Adipocytes under the skin help fight infections by producing an antimicrobial agent.

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image: A Movable Defense

A Movable Defense

By | January 1, 2015

In the evolutionary arms race between pathogens and hosts, genetic elements known as transposons are regularly recruited as assault weapons for cellular defense.

4 Comments

image: Stress Fractures

Stress Fractures

By | January 1, 2015

Social adversity shapes humans’ immune systems—and probably their susceptibility to disease—by altering the expression of large groups of genes.

6 Comments

image: The Year in Pathogens

The Year in Pathogens

By | December 29, 2014

Ebola, MERS, and enterovirus D68; polio eradication efforts; new regulations on potentially dangerous research

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image: Repurposed Retroviruses

Repurposed Retroviruses

By | December 18, 2014

B cells have commandeered ancient viral sequences in the genome to transmit antigen signals.

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image: Platelets Fan Inflammation

Platelets Fan Inflammation

By | December 4, 2014

The circulating blood cells bind to neutrophils, prompting inflammation-related activity in these immune cell partners.

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image: Gut Microbes Trigger Malaria-Fighting Antibodies

Gut Microbes Trigger Malaria-Fighting Antibodies

By | December 4, 2014

A carbohydrate antigen found on cells of E. coli and other species prompts a potent immune response against malaria-causing parasites in mice.

1 Comment

image: All Systems Go

All Systems Go

By | December 1, 2014

Alan Aderem earned his PhD while under house arrest for protesting apartheid in South Africa. His early political involvement has guided his scientific focus, encouraging fellow systems biologists to study immunology and infectious diseases.

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