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tag mouse research ecology genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Illustration showing mouse being injected with AAV mixture
Infographic: Taking AAV screening to the next level
Mariella Bodemeier Loayza Careaga, PhD | Mar 8, 2024 | 2 min read
DNA barcodes in AAV vectors technology simplified AAV screening.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
An Edith’s checkerspot butterfly
Genome Spotlight: Edith’s Checkerspot Butterfly (Euphydryas editha)
Christie Wilcox, PhD | Aug 25, 2022 | 3 min read
A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
a black abalone on a rock
Genome Spotlight: Black Abalone (Haliotis cracherodii)
Christie Wilcox, PhD | Jun 23, 2022 | 3 min read
The researchers who constructed the first reference genome for this critically endangered mollusk say it will assist restoration efforts.
The Scientist Staff | Mar 29, 2024

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