mouse research

Housing laboratory mice with those reared in a pet store makes the lab rodents’ immune systems more similar to those of people.

The maternal gut microbiome guides neo- and postnatal immune system development, a mouse study shows. 

Alterations in epigenetic markers on the X chromosome may be why males outnumber females among murine offspring bred through in vitro fertilization.

Researchers devise a technique for creating gametes from murine embryonic stem cells.

Behind the Theranos investigation; data-sharing beyond Zika; NCI to replace some cell lines with mouse avatars

Inhibiting the activity of a protein involved in the body’s stress response can ease chronic pain in mice.

Researchers should pay closer attention to the diets they use to study obesity in mice, experts advise.

Another study finds that housing experimental mice at lower-than-optimal temperatures may alter research outcomes, this time with regard to inflammation and diet.

Can mice with humanlike tissues better model drug effects in people?

The antioxidant found in red wine and some berries shows that small doses have more potent antitumor effects than large doses in a mouse model.

A European consortium identifies phenotypes for 320 genes, assigning new functions for half.

Ethical issues attend the creation of animal-human chimeras.

The brain contains lymphatic vessels similar to those found elsewhere in the body, a mouse study shows.

Data from three mice suggest months in space can alter the thickness and gene expression pattern of the skin.

Researchers identify a protein linked to excessive consumption of alcohol in animal models.

Researchers use chemicals to manipulate the behavior of mice.

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

Scientists have defined mouse neurons responsible for excessive food consumption at an unprecedented level of detail. 

British geneticist Mary Lyon has passed away at age 89.