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tag avian flu evolution cell molecular biology

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Study doubles avian flu genetic data
Susan Brown (sbsciwrite@sbcglobal.net) | Jan 26, 2006 | 3 min read
Genomic analysis of database might point to deadly mutations
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Unexpected Origin of an Avian Virus
Ruth Williams | Aug 26, 2013 | 3 min read
The transmission of reticuloendotheliosis viruses from mammals to birds was most likely an unexpected consequence of medical research.
an immune cell in blood
Why Viral Infections Are More Severe in People with Down Syndrome
Andy Carstens | Oct 14, 2022 | 6 min read
In people with the genetic condition, inflammation can cause a mild infection to snowball out of control, a study finds.
Single-handed flu combat?
Tia Ghose | Feb 22, 2009 | 3 min read
A single antibody may soon provide a one-size-fits-all antiviral for multiple strains of influenza. Researchers in the online version of Nature Structural and Molecular Biology have identified a human antibody that disarms the flu virus by jamming the machinery it uses to fuse with host cells. Hemagglutinin and antibody in complex Image: William Hwang Genes that code the influenza surface protein hemagglutinin are constantly reshuffled and tweaked, helping the virus hide from the immune syst
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Outsmarting Influenza's Rapid Evolution
Philip Hunter | Jun 29, 2003 | 7 min read
Twice yearly, World Health Organization health officials meet to strategize against influenza, a malady that kills at least 250,000 people each year. In a chess match of sorts, they work to predict their opponent's next move, in this case by modifying vaccines to compensate for changes in the critical viral antigen hemagglutinin, which triggers the host's long-term immune memory. It takes several months to manufacture and distribute flu vaccines in sufficient quantities to inoculate vulnerabl
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A single pathway for lung damage
Edyta Zielinska | Apr 16, 2008 | 2 min read
SARS, avian flu, and other lung diseases destroy the lungs via a common mechanism, researcher report in __Cell__ today. That mechanism, based on innate immunity, could provide new targets for treating severe lung damage, the linkurl:researchers say.;http://www.cell.com/content/article/abstract?uid=PIIS0092867408003401 Joseph Penninger, from the Institute of Molecular Biotechnology of the Austrian Academy of Sciences, and colleagues set up an intensive care unit for mice in his lab in order t

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