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tag immune rejection immunology cell molecular biology culture

Molecular Trigger for Organ Rejection in Mice Identified
Diana Kwon | Jun 27, 2017 | 2 min read
The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  
Image showing monoclonal antibody treatment
The Resilience of Monoclonal Antibodies and their Makers
Laura Tran, PhD | Mar 15, 2024 | 10+ min read
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
Toward Preventing Transplant Rejection with Immunologically Matched Stem Cells
Ruth Williams | Sep 15, 2016 | 3 min read
Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist and MilliporeSigma | Jul 18, 2022 | 3 min read
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
Immunology
The Scientist Staff | Jan 5, 1992 | 1 min read
Date: January 6, 1992, pp.16 S.H.E. Kaufmann, "Heat shock proteins and the immune response," Immunology Today, 11:129-36, 1990. (IMMUNOLOGY) Stefan H.E. Kaufmann (University of Ulm, Germany): "I assume that until recently most of my colleagues working in immunology associated the term `stress' with the feelings one has when an experiment does not work well or when a paper has been rejected. "Cell biologists earlier had found that cells show a stress response that very much resembles our own
Artist’s rendition of red SARS-CoV-2 coronaviruses floating near blue strands of DNA.
COVID-19 Infections May Reshape Genetic Landscape
Holly Barker, PhD | Mar 30, 2023 | 3 min read
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 
Immunology
The Scientist Staff | Nov 22, 1998 | 4 min read
K.C. Garcia, M. Degano, R.L. Stanfield, A. Brunmark, M.R. Jackson, P.A. Peterson, L. Teyton, I.A. Wilson, "An alpha-ß T cell receptor structure at 2.5Å and its orientation in the TCR-MHC complex," Science, 274:209-19, 1996. (Cited in more than 240 papers since publication) Comments by Ian A. Wilson, professor of molecular biology at The Scripps Research Institute in La Jolla, Calif. D.N. Garboczi, P. Ghosh, U. Utz, Q.R. Fan, W.E. Biddison, D.C. Wiley, "Structure of the complex bet
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
immune cells t cell natural kill cell cardiac stem cell ipsc
Gene Editing Makes Cells Evade Immune Attack In Vitro
Emma Yasinski | Dec 12, 2019 | 3 min read
To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.
Understanding Hybridoma Technology for Monoclonal Antibody Production
Understanding Hybridoma Technology for Monoclonal Antibody Production
Alpana Mohta, MD | May 9, 2023 | 5 min read
By fusing antibody-producing cells with immortal myeloma cells, researchers produce reliable supplies of highly specific antibodies.

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