autophagosome

Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how the gut maintains itself.

Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.

The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.

Loss of the protein ATG7 is fatal in mice, but not always for people—although it is linked to human neurodevelopmental disorders, researchers report.

From cellular self-digestion to the effects of exercise on the brain, our features editor picks her favorite art custom-made for the magazine.

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

Researchers identify receptors that target the endoplasmic reticulum for degradation by autophagy in yeast and mice. 

There are five steps of autophagosome biogenesis: induction, expansion, vesicle completion, fusion, and cargo degradation. 

Digestion on the cellular level: two mysteries examined

Despite years of research, the longstanding mystery of where the autophagosome gets its double lipid bilayers is not much clearer.