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tag amyloid plaques microbiology disease medicine

Do Microbes Trigger Alzheimer’s Disease?
Jill U. Adams | Sep 1, 2017 | 10 min read
The once fringe idea is gaining traction among the scientific community.
Artist’s rendition of a neuron silhouetted against a glowing red background.
SNO-y Protein Levels Help Explain Why More Women Develop Alzheimer’s
Dan Robitzski | Jan 6, 2023 | 4 min read
Female postmortem brains contain more S-nitrosylated C3 proteins, likely linked to menopause, which instruct immune cells to kill neuronal synapses.
Tau Ligand Reveals Tangles In Vivo
Kerry Grens | Sep 18, 2013 | 3 min read
In living humans, researchers image snarls of tau, one of the proteins associated with Alzheimer's disease.
Eyes, Nose as Windows to Alzheimer’s
Kerry Grens | Jul 14, 2014 | 2 min read
Failing a sniff test or screening positive on an eye exam may predict people’s chances of developing the neurodegenerative disorder.
Far-Out Science
Mary Beth Aberlin | Sep 1, 2017 | 3 min read
How psychedelic drugs and infectious microbes alter brain function
Researchers Homing In On Mechanisms Of Encephalopathic Diseases
Karen Young Kreeger | Jun 9, 1996 | 10+ min read
Encephalopathic Diseases One of the great biomedical quests of the last 20 years surrounds a handful of rare and mysterious brain diseases that affect humans and a small group of other mammals. An ongoing international research effort is aimed at understanding the mechanism of these neurodegenerative diseases. Recently, this area has been of particular relevance because one of the disorders-mad cow disease-has become a major, well-publicized health problem in Europe. Four encephalopathic disea
Inflammation's infamy
Karen Kreeger | Jul 13, 2003 | 9 min read
Courtesy of Keith Crutcher IMMUNITY IN MIND: Cultured microglial (N9) cells (red) on a tissue section containing an Alzheimer plaque (green). There is continuing controversy about whether these types of inflammatory cells are responding to plaques or causing them. A finger catches the sharp edge of an envelope; a noseful of tree pollen is accidentally inhaled; the latest virus finds host after human host. In all cases the assaulted body reacts through inflammation, a well known, but not
Week in Review: May 23–27
Tracy Vence | May 27, 2016 | 2 min read
Potential link between microbial infection and Alzheimer’s disease; CRISPR-enabled cell lineage tracing; image irregularities lead to anticipated retraction; brain glucose metabolism and consciousness; exploring emotional contagion; Zika-related microcephaly risk estimated
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016 | 10+ min read
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
X-ray Vision in Structural Genomics
Gregory Smutzer | Jun 10, 2001 | 10 min read
Updated! Suppliers of Tools for X-ray Crystallography Courtesy of Amersham Pharmacia BiotechDetail of the electron density map of deacetoxycephalosporin C synthase from Streptomyces clavuligerus. Two important approaches can be used to determine the three-dimensional structure of macromolecules. Nuclear magnetic resonance (NMR) spectroscopy yields information on the structure of proteins in solution, but it has a size limitation of approximately 150 amino acid residues (about 16,500 daltons),

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