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tag book reviews microbiology genetics genomics

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Researchers Blast Open Pathogen Genome
Barry Palevitz | Aug 18, 2002 | 6 min read
Image: Courtesy of Tim Elkins BRUTE FORCE: Remnant of an appressorium formed on Mylar. The appressorium produced a peg-like extension that penetrated the film, leaving a round hole. (Reprinted with permission, Annual Review of Microbiology, 50:491-512, 1996.) "The Lord shall smite thee with a consumption, and with a fever, and with an inflammation, and with an extreme burning, and with the sword, and with BLASTING, and with mildew; and they shall pursue thee until thou perish." Deuteronom
Writing Book Chapters Broadens the Scientific Experience
Ricki Lewis | Jun 21, 1998 | 8 min read
MIXED REVIEW: David Gordon, a science writer and biologist, calls chapter writing "a wonderful and awful experience." Scientists are, by necessity, writers. Academic scientists write exams, grant applications, and research papers; their industrial counterparts compose company reports and patent applications. Chapter writing offers a breather from these higher-pressure literary demands, whether it is for a published version of a symposium talk, a chapter for a textbook, or an analysis of a spec
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Software Helps Researchers In Sorting Through The Human Genome
Ricki Lewis | Jul 21, 1996 | 10 min read
The Human Genome SIDEBAR : Selected Suppliers of Software for Gene Discovery and Analysis Genetics has been an informational science since the elucidation of DNA's structure. Today's researchers say the field shifted to a more computational mode in 1990-the year that research groups began mapping genes to specific chromosomal sites for the Human Genome Project. "That year was pivotal, because it was then that the need to sequence significant amounts of DNA became compelling," says Richard Gib
Switch Master: A Profile of Barbara Meyer
Diana Kwon | Jan 13, 2020 | 9 min read
Working with bacteriophages and nematodes, the University of California, Berkeley, molecular biologist uncovered a role for genetic switches in early development.
The Garden of Antimicrobial Delights
Julian Davies | May 1, 2010 | 5 min read
By Julian Davies The Garden of Antimicrobial Delights Major advances in genomics, cloning, and chemistry will restock the dwindling supply of effective antibiotics, but we can’t depend on big pharma and biotech. Green mold hyphae and fruiting structure, Aspergillus ustus. Dennis Kunkel Microscopy, Inc. / Visuals Unlimited, Inc. Almost all papers and reviews dealing with infectious diseases stress that new classes of antibiotic
According to Protocol
Barbara Cunningham | Apr 15, 2001 | 8 min read
Nearly all scientists involved in basic biomedical research are familiar with the "Red Book" (Current Protocols in Molecular Biology)1 and Molecular Cloning: A Laboratory Manual.2 These well-known, time-tested books are still considered "bibles" in research laboratories, containing a wide range of basic techniques used by most life scientists. However, as scientific studies and experimental designs become more intricate and specialized, so do the techniques involved. As a result, detailed, "spec

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