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tag brown fat cell molecular biology ecology

Treating Fat with Fat
Edyta Zielinska | May 1, 2012 | 7 min read
Is brown fat ready for therapeutic prime time?
Brain’s Role in Browning White Fat
Anna Azvolinsky | Jan 15, 2015 | 4 min read
Insulin and leptin act on specialized neurons in the mouse hypothalamus to promote conversion of white to beige fat.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Fat-busting protein
Tudor Toma(t.toma@ic.ac.uk) | Oct 3, 2001 | 1 min read
The protein 4E-BP1 converts white adipose tissue into brown adipose tissue and consequently reduces obesity.
The Skinny on Fat Cells
Anna Azvolinsky | Nov 1, 2015 | 8 min read
Bruce Spiegelman has spent his career at the forefront of adipocyte differentiation and metabolism.
Flipped Fat-burning Linked to Cancer Cachexia
Jyoti Madhusoodanan | Jul 22, 2014 | 2 min read
Conversion of white fat to brown is associated with muscle atrophy and weight loss in cancer patients.
Fat's Immune Sentinels
Justin Odegaard and Ajay Chawla | Dec 1, 2012 | 10 min read
Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.
The Skinny Fat
Bruce Spiegelman | Jan 1, 2008 | 8 min read
The Skinny Fat FRANKLYN RODGERS / SCIENCE PHOTO LIBRARY All Fat Cell images courtesy of Patrick Seale What if you could make fat cells burn energy rather than store it? By Bruce Spiegelman Related Articles Energy-burning baby fat Two paths for a preadipocyte From an outsider's perspective, obesity seems like a simple problem to solve: Eat less, exercise more. But, the body regulates food intake and feelings of satiety as part of a tightly regulated home
Investigating Molecular Motors Step by Step
Jeffrey Perkel | Mar 14, 2004 | 10+ min read
Thom Graves MediaThe audience, several hundred biophysicists strong, was not expecting a James Brown impersonation. But there he was: Physiologist Yale Goldman, keynote speaker on motility at the Biophysical Society's annual meeting, doing his "asymmetric hand-over-hand motility dance with a limp" to tinny strains of "Papa's Got a Brand New Bag." And while Goldman, who eschewed Brown's trademark, over-the-top couture for understated, Ivy League-issue khakis and blue blazer, won't star on MTV any

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